Annie Whittington Cadle was the sixth daughter of William Cadle and Ann Whittington. Annie was born in Bristol, Gloucestershire, about 1871. At 10 years of age she and her younger sister Dora were boarders at a Commercial Travellers' School in Harrow, Middlesex. Two older sisters Minnie and Elsie were living at the Royal Asylum of St Anne's Society in Wandsworth, while two younger sisters Edith and Gladys were in the Infant Orphan Asylum in West Ham.
The family presumably came out to Australia for a better life. However, Elsie died at Ulverstone, Tasmania, in Mar 1889 at the age of 19. Annie and Gladys both took up nursing as a career. Annie, dressed here in her nurses' uniform, commenced her training at the Launceston General Hospital on 1 Sep 1891, but was dismissed on 1 Feb 1893. Ten years later she was nursing in Sydney, in 1914 she was in Frankston, Victoria, and by 1928 she had moved to Swansea in Tasmania where she undertook bush nursing. Annie died in Hobart on 18 Sep 1964 aged 93.